Could Omega-3 beat Vitamin D in preventing Autoimmune Disease?

A recent study compared the protective potential of Omega-3 versus Vitamin D in reducing autoimmune disease risk. It was conducted over 2 years and included 21,592 participants of both genders.

While a dose of 2000IU/day of vitamin D initially helped prevent autoimmune diseases, its effect attenuated over time. On the other hand, 1,000 mg/day of Omega 3 (n-3) fatty acids supplements have continued to offer a sustained reduction in the risk of developing autoimmune disease. Thus, Omega-3 revealed superiority.

More than 100 different conditions, such as celiac disease, vitiligo, type 1 diabetes, scleroderma, multiple sclerosis, lupus, rheumatoid arthritis and psoriasis are classified as autoimmune chronic diseases. These chronic conditions develop when the body's immune system mistakenly attacks healthy body parts.

References:

Costenbader, K., Cook,N., Lee, I., Hahn, J., Walter, J., Bubes, V., Kotler, G., Yang, N., Friedman, S.,

Alexander, E. & Manson, J. (2024). Vitamin d and marine n-3 fatty acids for autoimmune disease prevention: Outcomes two years after completion of a double-Blind, placebo-controlled trial. Arthritis and rheumatology.